This Clinical Research Group strengthens the neuroscientific focus of the medical faculty of the University of Göttingen. It combines a clinically-oriented expertise in genomics, pharmacogenomics, and (endo)phenomics of psychosis (WP1, WP2, WP3) with internationally renowned experience in molecular biology, epigenomics, systemic neurosciences (WP4, WP6). WP1 and WP2 have furthermore a long-standing experience in performing large-scale clinical studies on psychosis. This joint expertise is complemented by an outstanding component of genetic epidemiology and statistics (WP5).
• Prof. Dr. med. Marcella Rietschel, Department of Genetic Epidemiology, Central Institute of Mental Health, Mannheim, Germany (control samples, biobanking, phenotype databases, genotype-phenotype dissection analyses)
• Prof. Dr. med. Markus M. Nöthen, Prof. Dr. rer. nat. Sven Cichon, Department of Genomics of the Life & Brain Center and Institute of Human Genetics, University of Bonn (genomewide genotyping)
• Dr. Francis J. McMahon, Genetic Basis of Mood and Anxiety Disorders, NIMH, NIH, Bethesda, MD, USA (methodology, analysis, phenome databases)
• Dr. James B. Potash and Dr. J. Raymond DePaulo, Department of Psychiatry and Behavioral Sciences, The Johns Hopkins University, Baltimore, MD, USA ((methodology, analysis, phenome databases, future epigenetic profiling)
• Prof. Jim van Os, Dr. Inez Myin-Germeys, Faculty of Health, Medicine and Life Sciences, University of Maastricht, Maastricht, The Netherlands
• Dr. George Karypis, Department of Computer Science, The University of Minnesota, Minneapolis, MN, USA (data mining approaches)
• Dr. Nicholas J. Schork, Scripps Genome Research, San Diego, CA, USA (MDMR analysis for genotype-phenotype dissection)